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OSE Immunotherapeutics Announces Granting of First European Patent Protecting Anti-IL-7 Receptor Antagonist OSE-127/S95011

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OSE Immunotherapeutics Announces Granting of First European Patent Protecting Anti-IL-7 Receptor Antagonist OSE-127/S95011


OSE Immunotherapeutics Announces Granting of First European Patent Protecting Anti-IL-7 Receptor Antagonist OSE-127/S95011 – Book Publishing Industry Today – EIN Presswire




















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EU asks Hungary to keep liberal radio station on the air

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EU asks Hungary to keep liberal radio station on the air

The European Union’s executive has urged the government in Hungary to allow a liberal-leaning radio station to continue broadcasting after it went off the air on Monday.

Klubrádió went off the airwaves on Sunday at midnight after a court upheld a decision by media authorities not to extend its broadcasting licence.

During an online press conference of the European Commission on Monday, spokesman Christian Wigand confirmed the executive had sent a letter to Hungary’s permanent representation in Brussels on Friday expressing its concerns over the move.

Wigand said the station’s loss of its broadcasting frequency had occurred “on the basis of highly questionable legal grounds”, and that Hungary “should respect the EU’s charter of fundamental rights, including the rights to freedom of expression, information and the freedom to conduct a business”.

The Commission has asked Hungary to take urgent action to ensure that Klubrádió, a commercial broadcaster in the capital of Budapest, can continue using its frequency until final decisions become legally binding, Wigand said, warning of “irreparable damage” to the station.

Hungary has not yet sent an answer to the Commission’s letter, the spokesman added.

But Balázs Hidvéghi, a Member of the European Parliament from the country’s ruling Fidesz party, explained that media organisations must respect the rules.

“Quite frankly Klubradio, as well as other radio stations or media outlets have to respect the law and have to operate according to the law in Hungary,” he explained to Euronews.

“The media authority has not renewed automatically the frequency for this radio station because they broke some of the regulations that they should have respected.”

The Communication sent by the Berlaymont comes after more than eighty MEPs sent their own communication to the Commission last Friday, asking for it to take action over media woes in both Hungary and Poland.

The main author of the letter, Laurence Farreng, told Euronews that: “We can’t let down this battle for rule of law. I think everything we can do has to be done. So, I follow very closely the media action plan that was proposed by the European Commission.

“In this media action plan, media pluralism, freedom of speech, media recovery is at the heart of the project. So, I think there is a point where we can act to ask for more freedom and more funding for the media,” the French MEP added.

The loss of Klubradio’s broadcasting licence reinvigorated a debate over freedom of the press and outsized political influence in Hungary’s media market.

The liberal-leaning commercial station was one of the only remaining opposition radio voices in Hungary and one of the last radio channels that regularly featured opposition politicians and other critical voices during its news and talk programmes.

The European Commission last Wednesday denounced the decision, saying the move “increases concerns” about “media freedom and pluralism” in Hungary.

Klubrádió’s president Andras Arato last week cited authorities as saying the station had “broken the rules” when the media lost its licence.

Arato denounced Tuesday’s decision as “a shameful decision”, which raises new concerns about press freedom in this European Union country.

He told Euronews that he planned to appeal to Hungary’s highest court, the Curia, promising that his media would continue online and that listeners were “keen”.

“We will not be silenced, and if they also want to support us, we will try to do our bit so we can live in a better world,” he said.

Michael McDowell: EU chilly on State’s ‘soft cop’ NI protocol line

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Michael McDowell: EU chilly on State’s ‘soft cop’ NI protocol line

Nothing is as simple as it seems in relation to Covid and the Northern Ireland protocol. The Financial Times reported this week that anonymous EU sources were voicing annoyance with recent efforts by Micheál Martin and Simon Coveney to persuade Brussels and London to dial down the heat in relation to the practical problems that have arisen in implementing the customs aspect of the protocol as they affect British goods going into Northern Ireland.

                                                    <p class="no_name">Apparently there is some resentment in certain circles in Brussels that Ireland seems to be acting as an intermediary rather than as a fully-fledged cheerleader for the hardline rhetoric coming from the Berlaymont.</p>
                                                    <p class="no_name">The paper quoted one EU diplomat as saying: “There is a growing concern that Dublin is tempted to follow a policy of equidistance towards the EU and UK on Northern Ireland.”</p>
                                                    <p class="no_name">The same source, recalling the EU’s steadfast support for Ireland in the Brexit process, added that “it would be rather risky if the Irish Government were to be seen as playing with European goodwill and solidarity”.</p>
                                                    <blockquote class="inline__content inline__content--pullquote">

It bears repetition that the attempted invocation of the protocol was utterly unlawful

These ominous noises come ill from the EU Commission. Exactly who played fast and loose with the protocol in the first place?

                                                    <p class="no_name">While Ursula Von Der Leyen sandbagged her commission with personal acceptance of responsibility for the shocking misuse of the protocol as stage furniture in its spat with the UK over vaccine exports, the sad fact remains that the episode went unexplained.</p>
                                                    <p class="no_name">Nor did she help by departing the EU parliament last week to hold another evasive press conference before MEPs could extract any explanation.</p>
                                                    <p class="no_name">It bears repetition that the attempted invocation of the protocol was utterly unlawful – even as a matter of EU law. The protocol simply never covered exports of vaccine at all.</p>

                                                                                                        <aside class="related-articles--instream has-3">

                </aside>


                                                                <p class="no_name">Moreover, the terms of the protocol and its 7th annexe clearly prohibited its abrupt unilateral invocation in these circumstances even if it had any application to vaccine exports – which it didn’t.</p>
                                                    <p class="no_name">In addition, the protocol itself provides for consultation in respect of the entirely different issues in relation to customs documentation and grace periods.</p>
                                                    <h4 class="crosshead">Confrontation</h4><p class="no_name">Dublin has every right to seek to defuse confrontation when hard-line exchanges and position-taking play directly into the hands of DUP irredentism and would-be back-sliders in the Tory party at Westminster.</p>
                                                    <p class="no_name">And unexplained gross misuse of the protocol at senior level in the commission gave Dublin every reason to want to cool the temperature and ensure that the protocol’s customs arrangements in Northern Ireland bedded down smoothly and pragmatically.</p>
                                                    <figure class="inline__content inline__content--image"> 
Ursula Von Der Leyen: she may be trying to pressurise the UK over vaccine-sharing and other issues. Photograph: Getty Images

No one in Europe, with the possible exception of those personally to blame for the debacle, could have any complaint with the response of the Irish Government which was uniquely passive compared to what any other member state – big or small – would have done in similar circumstances.

                                                    <p class="no_name">This makes anonymous EU warnings published in the Financial Times coverage all the more difficult to accept at face value.</p>
                                                    <blockquote class="inline__content inline__content--pullquote">

The reality is that the EU may end up with recovery delayed by at least half a year behind the UK and other countries

It raises the possibility that what we are witnessing is but a glimpse of a deeper bout of arm-wrestling between the commission and the UK in which the Irish issues are a mere sideshow.

                                                    <p class="no_name">The commission may be playing “hard cop” in a wider conflict over vaccine-sharing and other issues, including the UK’s persistent demands to have continued access to EU financial markets without acceptance of EU rule-making authority in that sphere.</p>

                                                    <p class="no_name">On the issue of vaccines, for all the rhetoric about caution and the community method the reality is that the EU may end up with recovery delayed by at least half a year behind the UK and other countries.</p>
                                                    <p class="no_name">The social and economic cost of such massive delay is enormous, and may well become politically unsustainable. The reputation of the commission and other EU institutions is very much in issue. The European Centre for Disease Prevention and Control warnings about virus-mutation risks add to the pressure.</p>
                                                    <h4 class="crosshead">Social damage</h4><p class="no_name">Playing “hard cop” with the UK may be part of a wider process in which the commission hopes to radically cut the time-delay gap in order to minimise the economic and social damage of having lockdown restrictions carry over into the autumn.</p>
                                                    <p class="no_name">Sharing vaccine production and accelerating it may be a political imperative at EU level that puts concern for the Good Friday agreement in the halfpenny place.</p>
                                                    <p class="no_name">If EU’s diplomats now want to ratchet up the heat in pursuance of these agenda items, Irish calls to cool it may appear disloyal, much the same as Michael Corleone in the Godfather had to slap down his brother Fredo’s appeals for moderation in their dealings with rival families.</p>
                                                    <p class="no_name">High-minded concern for the Good Friday agreement and an open Irish Border matter far less now to an embattled commission which is looking exposed and vulnerable in relation to a great delay in mass vaccination right across the EU.</p>
                                                    <p class="no_name">This is, after all, what realpolitik actually means.</p>

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New assessment shows high risk of introduction and spread from fur farming of the virus that causes COVID-19

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A global risk assessment conducted by the Food and Agriculture Organization of the United Nations (FAO), the World Organisation for Animal health (OIE) and WHO has shown that the overall risk of introduction and spread of the SARS-CoV-2 virus, the virus that causes COVID-19, from the fur-farming system to humans and to susceptible wildlife populations in the WHO European Region is considered high.

The global tripartite conducted the risk assessment in light of the Region’s high number of fur farms, the wide variety of susceptible animal species used in fur farming, and the high number of overall cases of COVID-19 reported among the human population.

WHO European Region – the largest producer of fur

It is well documented that the SARS-CoV-2 virus can transmit between humans and animals. In April 2020, the Netherlands was the first country to report SARS-CoV-2 in farmed minks. Since then, another 9 countries – 7 of which are in the European Region – have reported similar findings. The European Region includes the largest number of fur-producing countries of all WHO regions.

In November 2020, Denmark reported the detection of a mink-associated SARS-CoV-2 variant with a combination of mutations not previously observed (referred to as Cluster 5). Preliminary findings suggested a lower capability of antibodies to neutralize the strain, and isolates of the variant strain were shared with selected WHO reference laboratories.

Following these findings, WHO in collaboration with the European Centre for Disease Prevention and Control (ECDC) conducted a series of meetings with mink fur-producing countries as well as a survey about SARS-CoV-2 in mink farms in the European Region.

These efforts aimed to get an overview of the fur-farming industry in Europe, gather information about measures applied by countries to prevent and reduce virus transmission between humans and animals, and inform the development of the One Health risk assessment on SARS-CoV-2 in farmed fur animals.

Wide disparity in measures adopted across the Region

A total of 31 of the Region’s 53 Member States responded to the survey. Of these, 15 reported that they have a fur industry. The fur industry is dominated by minks, while chinchillas, sables, foxes, rabbits and racoon dogs make up a smaller proportion of farmed fur animals.

The collected information highlighted that measures and procedures vary widely from country to country. Fourteen of the 15 countries with a fur industry have implemented SARS-CoV-2 surveillance systems on fur farms. Nine countries have implemented surveillance systems to detect the virus in humans who work on the farms, and 8 have detected SARS-CoV-2 in mink farm workers.

Nine countries also reported that they analyse for variations in DNA sequences of SARS-CoV-2 viruses in animals, while 8 countries analyse for variations in DNA sequences of SARS-CoV-2 virus isolates detected in humans. The analyses have identified several combinations of mutations in mink-associated variants across countries.

The information also showed that both mandated and recommended biosecurity measures to prevent transmission of SARS-CoV-2 between animals and humans differ considerably across countries in the Region. This includes requirements for the use of personal protective equipment (PPE), access to the farms, and movement of animals and workers between farms.

Strict procedures needed

To prevent and reduce further spread between humans and fur-farmed animals, the One Health risk assessment provides a series of recommendations, in particular to:

  • enforce strict sanitary biosecurity measures against SARS-CoV-2;
  • provide and ensure the use of appropriate PPE by farm workers and visitors;
  • consider risk-based testing of animals for SARS-CoV-2 within the broader response to COVID-19;
  • sample and test susceptible wild species and other free-roaming animals in the vicinities of SARS-CoV-2-infected fur farms;
  • prevent farm workers with COVID-19 symptoms from entering farm premises;
  • conduct whole genome sequencing of viruses from human and animal cases and share virus isolates; and
  • enhance surveillance for COVID-19 at the animal–human interface where susceptible animal reservoirs are identified, including fur farms.

About One Health

One Health is an approach to designing and implementing programmes, policies, legislation and research in which multiple sectors communicate and work together to achieve better public health outcomes. The One Health approach is critical to addressing health threats at the animal–human–environment interface, and is particularly relevant to

  • food safety
  • control of zoonotic diseases
  • laboratory services
  • neglected tropical diseases
  • environmental health
  • antimicrobial resistance.

EU records 450,000 excess deaths between March and November

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EU records 450,000 excess deaths between March and November

Countries in the European Union recorded over 450,000 excess deaths between March and November 2020, compared to the same period in the past four years, according to data released on Tuesday.

The data “gives a general measure of the mortality impact of the COVID-19 pandemic because it includes all deaths independently of their causes” statistics agency Eurostat said.

“The data covered in this analysis include all deaths that have occurred from January to November 2020,” it said.

First wave

Eurostat used monthly data from all EU countries, except Ireland which didn’t provide data, to compare excess mortality in 2020 to a baseline of the average number of deaths recorded in the same period between 2016 to 2019.

“During the early rise of COVID-19, the excess mortality in the EU reached its first peak in April 2020, with an increase of 25% compared with the average of the same month over 2016 – 2019,” the agency said.

In April, when the first wave of the pandemic was at its peak, Spain saw close to 80% increase in the average deaths whereas Belgium saw deaths sitting at almost 74% above the average.

November peak

“Between May and July, a lower level of excess mortality was registered, while yet another surge in mortality started in August – September with the next wave of the pandemic,” Eurostat said.

“The excess mortality in the EU was 8% above the average in September, +17% in October and +40% in November, with the indicator rising in all EU Member States.”

The November peak was particularly deadly for Poland, Slovenia, and Bulgaria, with each of them recording an increase of 90 percent.

Belgium also saw a nearly 60% increase, while both Italy and Austria neared a 50% increase.

Eurostat, however, stressed that while the substantial increase coincided with the pandemic, “the indicator does not discriminate among the causes of death and does not catch differences across sex and age classes.”

DPA contributed to this report.

EU court rejects Ryanair lawsuit against airline state aid

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EU court rejects Ryanair lawsuit against airline state aid

Ryanair on Wednesday lost a legal fight in the European Union’s second court against state aid being granted to pandemic-hit rivals Air France and Sweden ‘s SAS through national schemes.

Judges at the EU’s General Court in Luxembourg backed EU competition regulators who had allowed the support under loosened rules.

What was Ryanair’s complaint?

Thestate aid rules of the European Commission — the defendant in the case —were loosened at the start of the pandemic.

National governments offered more than 3 trillion euros ($3.65 trillion) in aid to companies across the 27-member bloc.

The General Court was asked to assess a French scheme allowing airlines to defer certain aeronautical taxes, and to rule on Sweden’s loan guarantee scheme for airlines.

Ryanair has pursued a legal campaign across Europe to stop the bailouts, arguing the state aid gives an unfair advantage to prestigious national flag carriers.

What did the court say?

“This aid scheme is appropriate to remedy the economic damage caused by the COVID-19 pandemic and does not constitute discrimination,” the court said, referring to the French scheme.

It also said the Swedish scheme was compatible with EU laws. The court said that the limitation of the loan guarantee scheme “is appropriate for achieving the objective of remedying the serious disturbance in Sweden’s economy.”

What can the Irish airline do now?

The losses for Ryanair were just a first round, and the cases could now moving to the higher European Court of Justice.

Ryanair — the biggest airline in Europe when it comes to passenger numbers — is also seeking to reverse Germany’s massive bailout of Lufthansa.

It also has lodged proceedings against the commission over the Netherlands’ KLM, Austrian Airlines and Portugal’s TAP, among others.

rc/rt (Reuters, AFP)

If you like this TV show, read this book

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If you like this TV show, read this book


During the past few years, the number of books I’ve read has dwindled, while the amount of shows I’ve binge-watched has skyrocketed. It’s a lot easier to be drawn to the remote, but books are an equal, if not better, source of entertainment. They carry the same appeal but hold so much more content than the screen could ever portray. Plus, reading provides you with the opportunity to visualize characters yourself. Sure, you’re given a basic description of what they look like, but it allows far more interpretation than being fed an actor or actress some casting director deemed fit for the role.  

That all being said, sometimes it can be difficult to choose a book that will capture your attention. By looking at your taste in television shows, you can get a better picture of what kind of book you’d like to read. So here are some of my recommendations to you. 

“The Bachelor” 

If you love all the drama that comes with “The Bachelor,” there’s no doubt you’ll love “The Selection” series by Kiera Cass. The show isn’t really up my alley, but even I can admit there is something entertaining about a group of women battling over one guy. It’s very reminiscent of “The Hunger Games”; though there is less physical gore, there is certainly plenty of emotional warfare at play. 

“The Selection” features a face-off between a bunch of ruthless girls, not only seeking their way to a man’s heart, but vying for the crown. Every girl has dreamt of being a princess, right? America Singer, one of the 35 contestants, finds herself warring between a future with her forbidden love of a lower caste or a future with the prince. Either way, a life of luxury does not come so easily, as the palace is riddled with attacks, making this series essentially a dystopian version of “The Bachelor.” 

“The Great British Baking Show” 

If you’re into competitions more friendly in nature and are a fan of “The Great British Baking Show,” you might just find your mouth watering at the descriptions of Cath’s culinary creations in “Heartless” by Marissa Meyer. Though this book is a lot more fantastical than “The Great British Baking Show.” It features a character whose one goal in life is to open a bakery in Wonderland. Cath is constantly whipping up delectable treats, whether it be pumpkin cake, delicate rose macarons or lemon tarts made from a magical tree. The story even includes a baking competition, where the King of Hearts, rather than Paul Hollywood, judges the treats. 

“Outer Banks” 

Many people got swept up into “Outer Banks” at the start of quarantine, and I can’t blame them. The setting had such a unique vibe, and if you enjoyed it, chances are you’ll love “The Rest of the Story” by Sarah Dessen. I usually prod fun at the cheesy nature of Dessen’s stories, but this one makes me feel nostalgic for an experience I never actually had: summer at the lake. This contemporary novel takes place in a town where the lake is its most notable feature. The protagonist, Emma Saylor, is on the hunt for who her late mother really was, similar to John B’s quest to find out what happened to his father. There is also the interesting dynamic of a town divided by tourism, with half of the lake being home to rich tourists, while the other half live there year-round, working diligently just to make ends meet. This dynamic reminded me a lot of the tension between Pogues and Kooks in “The Outer Banks.” 

“The Society” 

This show is basically a modern-day version of my favorite piece of required reading, “Lord of the Flies.” Following a group of young schoolboys stranded on an island without any adult supervision whatsoever, they quickly become their own worst enemies, unable to work together towards a solution. The Society takes a similar turn, with high schoolers scavenging for signs of life, hoarding food and even poisoning one another as power dynamics shift.   

“You” 

Let’s be real, if you liked this show, you’d probably enjoy most psychological thrillers out there today. But a solid book to start with is “The Girl on the Train,” which follows a woman who becomes obsessed with a couple whom she sees on her daily commute to work. She becomes preoccupied envisioning what their lives are like, and when tragedy strikes, finds herself thrust into their actual story. 

“Mindhunter” 

I don’t know many people who watch “Mindhunter,” but it’s seriously amazing. It follows the creation and cultivation of the term “serial-killer,” with an investigative duo visiting and studying several convicted criminals who could potentially fall under this category. At one point, they actually visit Charles Mansfield, who is a huge part of the book “The Girls” by Emma Cline. The novel does an incredible job delving into the fascinating mindset of the members of his cult, depicting just how willing they were to go to unthinkable extremes. 

“Say Yes to the Dress” 

If you love this show, along with other TLC offerings, you’ll definitely love the family dynamic present in “Save the Date” by Morgan Matson. This book is filled with everything you could possibly imagine relating to the stress of wedding planning, from dealing with a big family and conflicting personalities to crushing on the wedding planner’s nephew. Just like in all of Matson’s books, the characters are extremely lovable and will definitely fuel your love of all things wedding.  

Ukraine joins EU’s decision to expand sanctions against Syrian regime

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Ukraine joins EU's decision to expand sanctions against Syrian regime

(MENAFN – UkrinForm) Ukraine has joined a decision of the Council of the European Union to impose restrictive measures against individuals and legal entities in connection with the situation in Syria.

This is said in the Declaration by the EU High Representative on behalf of all member states, published on the website of the Council of the EU, Ukrinform reports.

“On 15 January 2021, the Council adopted Decision (CFSP) 2021/30 implementing Council Decision 2013/255/CFSP. The Council added one person to the list of natural and legal persons, entities or bodies subject to restrictive measures in Annex I to Decision 2013/255/CFSP. The Candidate Countries the Republic of North Macedonia, Montenegro and Albania, and the EFTA countries Iceland, Liechtenstein and Norway, members of the European Economic Area, as well as Ukraine, the Republic of Moldova and Georgia align themselves with this Council Decision,” the declaration reads.

According to the document, these countries will ensure that their national policies conform to this Council Decision. The European Union took note of this commitment and welcomed it.

In May 2013, the Council of the EU agreed to adopt restrictive measures against Syria in the following fields: export and import restrictions with the exception of arms and related material and equipment which might be used for internal repression; restrictions on financing of certain enterprises; restrictions on infrastructure projects; restrictions of financial support for trade; financial sector; transport sector; restrictions on admission; and freezing of funds and economic resources.

By a decision dated January 15, 2021, the Council added the newly appointed foreign minister of Syria to the sanctions list.

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Big data: definition, benefits, challenges (infographics) | News | European Parliament

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Big data: definition, benefits, challenges (infographics) | News | European Parliament

, https://www.europarl.europa.eu/news/en/headlines/society/20210211STO97614/

EU new car registrations hit record low in January

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EU new car registrations hit record low in January

New car sales in the European Union fell steeply in January, hitting a record low for the month as coronavirus-related restrictions weighed, according to data published Wednesday.

Across the EU, new car registrations–a reflection of sales–fell 24% to 726,491 vehicles in January, according to the European Automobile Manufacturers’ Association, or ACEA. The figure is the lowest total for January on record, with pandemic-related restrictions continuing to affect sales. Most markets also had one less business day than the previous January.

A majority of countries in the bloc posted double-digit decreases in January, with Spain hardest hit at a decline of more than 50% on the year. In Germany sales were down 31%, and those in Italy fell 14%. France was the best-performing major market with a drop of 5.8%, while in Sweden sales were up 23%, making it the only EU country where the figure was positive.

Meanwhile, all major European auto makers saw sales decline on-year in January. Volkswagen AG experienced a decline of 27%, while two other German companies, Daimler AG and Bayerische Motoren Werken AG, recorded drops of 14% each. Sales at France’s Renault SA fell 22%, and sales at recently-formed Stellantis NV dropped 26%, based on comparable figures from last year for its constituent companies Fiat Chrysler and Peugeot.

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